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CiteSeerXDocument Details (Isaac Councill Lee Giles Pradeep Teregowda) 1 In vitro cellular responses to silicon carbide particles manufactured through the Acheson process impact of physico-chemical features on pro-inflammatory and pro-oxidative effects.
Get PriceToxicological Investigations on Silicon Carbide. 2. In
Toxicological investigations on silicon carbide. 2. In vitro cell tests and long term injection tests J Bruch B Rehn W Song E Gono W Malkusch Abstract Silicon carbide (SiC) dust and other dusts for comparison were injected intratracheally at a high dose (50 mg) into rats and the response of the lungs and die lymph nodes was studied
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Mar 01 1997 · In vitro cellular responses to silicon carbide particles manufactured through the Acheson process impact of physico-chemical features on pro-inflammatory and pro-oxidative effects. Boudard D Forest V Pourchez J Pourchez J Boumahdi
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Sep 14 2016 · Boudard D Forest V Pourchez J Boumahdi N Tomatis M Fubini B Guilhot B Cottier M Grosseau P (2014) In vitro cellular responses to silicon carbide particles manufactured through the Acheson process impact of physico-chemical features on pro-inflammatory and pro-oxidative effects. Toxicol In Vitro 28 856–865
Get PriceExposure to silicon carbide and cancer risk a systematic
Sep 14 2016 · Boudard D Forest V Pourchez J Boumahdi N Tomatis M Fubini B Guilhot B Cottier M Grosseau P (2014) In vitro cellular responses to silicon carbide particles manufactured through the Acheson process impact of physico-chemical features on pro-inflammatory and pro-oxidative effects. Toxicol In Vitro 28 856–865
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Apr 08 2010 · Abstract. J Mater Sci Mater Med (2010) 21 2141–2149 DOI 10.1007/s Nanosilicon carbide/hydroxyapatite nanocomposites structural mechanical and in vitro cellular properties • • Saeed Hesaraki Touraj Ebadzadeh Shaghayegh Ahmadzadeh-Asl Received 18 January 2010 / Accepted 18 March 2010 / Published online 8 April 2010 Springer Science Business Media
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After several in vitro and in vivo studies the bio- enough to allow for cell migration and ECM formation compatibility of the material has been demonstrated by yet not be so small that pore occlusion occurs.1 2 The testing the adhesion proliferation and osteoblastic scaffold surface architecture and chemistry should pro- activity in vitro
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The in vitro and in vivo data jointly support the notion that the addition of amorphous silicon carbide to the standard silicon probe is biocompatible and decreases the neuroinflammatory response to cortical implants by reducing the intensity of GFAP adjacent to the device.
Get PriceToxicological Investigations on Silicon Carbide. 2. In
Toxicological investigations on silicon carbide. 2. In vitro cell tests and long term injection tests J Bruch B Rehn W Song E Gono W Malkusch Abstract Silicon carbide (SiC) dust and other dusts for comparison were injected intratracheally at a high dose (50 mg) into rats and the response of the lungs and die lymph nodes was studied
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An in vitro study showed that silicon carbide prevents electron transfer to adhering cells and proteins much better than BMS. 36 In this study the aSiC H-coated stents increased the critical electron gap to >0.9eV leading to lower electron transfer into the stent material. These findings indicate that aSiC H coating can indeed act to
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Crystalline silicon carbide (SiC) and silicon (Si) biocompatibility was evaluated in vitro by directly culturing three skin and connective tissue cell lines two immortalized neural cell lines and platelet-rich plasma (PRP) on these semiconducting substrates. The in vivo biocompatibility was then evaluated via implantation of 3C-SiC and Si shanks into a C57/BL6 wild type mouse.
Get PriceIn Vitro and In Vivo Biocompatibility Testing of Silicon
The in vitro and in vivo data jointly support the notion that the addition of amorphous silicon carbide to the standard silicon probe is biocompatible and decreases the neuroinflammatory response to cortical implants by reducing the intensity of GFAP adjacent to the device.
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Recently silicon carbide has attracted the attention of researchers due to its higher biocompatibility compared to Si as assessed through preliminary in vitro 40 and in vivo 41 studies. The
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We determined the in vitro activity of three well‐characterized samples of silicon carbide whiskers and a continuous glass filament sample in four different cellular assays and compared this to the activities of UICC crocidolite JM Code 100 glass microfiber and erionite in the same assay systems.
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commonly silicon (as silicon carbide silicon dioxide silicon nitride) nanoparticles in human alveolar epithelial (HPAEpiC) and pharynx (HPPC) cell lines in vitro since inhalation is an important pathway for exposure to these nanoparticles. HPAEpiC and HPPC cells were treated with silicon (0 -100 µg/mL)
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Details on test system and experimental conditions For the pre-incubation method the following materials are mixed in a test tube and pre-incubated with the tester strains for 60 minutes at 37 °C 100µL Test extract at each dose level vehicle control negative control or reference mutagen solution (positive control) 500µL S9 mix (for testing with metabolic activation) or S9 mix
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Ultrason Sonochem carbide nanoparticles by azo radical initiators. J Phys 15(1) 55–64 Chem C 112(31) 11786–11790 Sager TM Porter DW Robinson VA Lindsley WG Schwegler- Iolitec (2007a) Silicon(IV)carbide—technical data sheet.
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In Vitro and In Vivo Biocompatibility Testing of Silicon Carbide for Neural Interfaces A Dissertation submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy at George Mason University by Gretchen L. Knaack Master of Arts George Mason University 2011 Director Joseph J. Pancrazio Professor
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Di erently-Terminated Ultra-Small Silicon Carbide Nanoparticles cluster formation as well as in terms of their influence on the overall cellular response 15–18 . As soon as any NP is administered into a biological fluid (a cultivation medium in vitro or blood in vivo) the particles form a new identity from the various components of the
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1 In vitro cellular responses to silicon carbide particles manufactured through the Acheson process impact of physico-chemical features on pro-inflammatory and pro-oxidative effects. Delphine Boudard abc Valérie Forest bd Jérémie Pourchez bd Najih Boumahdi be Maura Tomatis f Bice Fubini f Bernard Guilhot be Michèle Cottier abc Philippe Grosseau be
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Mar 01 2018 · In vitro cellular responses to silicon carbide particles manufactured through the Acheson process impact of physico-chemical features on pro-inflammatory and pro-oxidative effects Toxicol. In Vitro 28 ( 2014 ) pp. 856865
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Biomedical applications of mesoporous silica nanoparticles (MSNs) require efficient cellular uptake and low toxicity. The purpose of this study is to investigate the cellular uptake and toxicity of MSNs with different sizes and charges (50 100 and 250 nm with a positive surface charge and 100 nm with a negative surface charge) exposed to human monocyte-derived macrophages lung epithelium
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Delphine Boudard Valérie Forest Jérémie Pourchez Najih Boumahdi Maura Tomatis Bice Fubini Bernard Guilhot Michèle Cottier Philippe Grosseau. In vitro cellular responses to silicon carbide particles manufactured through the Acheson process Impact of physico-chemical features on pro-inflammatory and pro-oxidative effects.
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Sep 04 2012 · Bruch J Rehn B Song H et al (1993b) Toxicological investigations on silicon-carbide. 2 in vitro cell tests and long-term injection tests. Br J Ind Med 50(9) 807–813 Google Scholar Bruch J Rehn S Rehn B et al (2004) Variation of biological responses to different respirable quartz flours determined by a vector model.
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The development of nanotechnologies may lead to dissemination of potentially toxic nanoparticles in the environment. Toxicology of these nano-sized particles is thus attracting attention of public and governments worldwide. Our research is focused on the in vitro response of eukaryotic cells to nanoparticles exposure. For this purpose we used cellular models of primary target organs (lung
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Oct 17 2013 · Magnesium (Mg) is a promising biodegradable metallic material for applications in cellular/tissue engineering and biomedical implants/devices. To advance clinical translation of Mg-based biomaterials we investigated the effects and mechanisms of Mg degradation on the proliferation and pluripotency of human embryonic stem cells (hESCs). We used hESCs as the in vitro model system
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Silicon Carbide Biotechnology A Biocompatible Semiconductor for Advanced Biomedical Devices and Applications Second Edition provides the latest information on this wide-band-gap semiconductor material that the body does not reject as a foreign (i.e. not organic) material and its potential to further advance biomedical applications. SiC devices offer high power densities and low energy
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In many of our studies we chose biocompatible semiconductors such as silicon or silicon carbide nanostructures which can target a single cell or subcellular component (Table 1).Our methods have the potential to overcome the limitations of current metal electrode-based devices such as bulk and cell membrane disruption while avoiding the need for genetic modifications.
Get PriceIn Vitro Cytotoxicity and Molecular Effects Related to
commonly silicon (as silicon carbide silicon dioxide silicon nitride) nanoparticles in human alveolar epithelial (HPAEpiC) and pharynx (HPPC) cell lines in vitro since inhalation is an important pathway for exposure to these nanoparticles. HPAEpiC and HPPC cells were treated with silicon (0 -100 µg/mL)
Get PriceToxicological consequences of TiO 2 SiC nanoparticles
The development of nanotechnologies may lead to dissemination of potentially toxic nanoparticles in the environment. Toxicology of these nano-sized particles is thus attracting attention of public and governments worldwide. Our research is focused on the in vitro response of eukaryotic cells to nanoparticles exposure. For this purpose we used cellular models of primary target organs (lung
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